Understand Your Options
Learn the Facts About Doxil
Optimize Your DOXIL Therapy
Find the Support You Need
Important Safety Information
Prescribing Information

For Caregivers
For Healthcare Professionals
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DOXIL—Patient Video Patient Video

Please click the chapter links below to view the video.

Video

View Chapter 1: What is DOXIL?
For more information on DOXIL, visit Learn the Facts about DOXIL.

View Chapter 2: What Can Be Expected from DOXIL Therapy?
For more information on what to expect during your DOXIL therapy, visit Optimize Your Therapy.

View Chapter 3: Side Effects and How They Are Managed
For more information about the side effects associated with DOXIL therapy, visit Common Side Effects.

View Chapter 4: Hand-Foot Syndrome
For more information on how to help manage and prevent hand-foot syndrome, visit Managing Side Effects.

View Chapter 5: Stomatitis
For more information on how to help prevent stomatitis, visit Managing Side Effects.

View Chapter 6: Staying on Course
For more information on how you can stay on course with your treatment, visit Staying on Course.

Doxil (doxorubicin HCl), is a prescription medicine that is administered intravenously by your healthcare professional. DOXIL is used to treat patients with ovarian cancer that has progressed or recurred after platinum-based chemotherapy.

Please read Important Safety Information below, and talk to your healthcare professional to learn more about DOXIL.


Important Safety Information

Serious and possibly permanent heart-related side effects that may lead to congestive heart failure can occur in patients treated with DOXIL. Inform your doctor of any history of heart disease, radiation to your chest, or prior chemotherapy. Your doctor may monitor your heart function.

Infusion reactions may occur during administration. Be sure to tell your doctor if you have any symptoms during infusion, including: flushing, shortness of breath, facial swelling, headaches, chills, back pain, tightness in your chest or throat, dizziness, or lightheadedness. For most patients, these reactions have resolved within several hours to a day once the infusion is stopped, or for some patients with slowing of the infusion rate. However, in some cases, these reactions may be serious and sometimes life threatening, though they are rarely fatal.

DOXIL may severely reduce the number of blood cells (red blood cells, white blood cells, and platelets) in your body. Your doctor may adjust or delay your dose of DOXIL if this occurs.

Your doctor may adjust your dose of DOXIL if you have liver problems.

You should not take DOXIL if you are nursing. If you are pregnant or are planning to become pregnant, inform your doctor.

You should not take DOXIL if you are allergic to doxorubicin HCI or the components of DOXIL.

The most common side effects of DOXIL are:

  • Hand-Foot Syndome (HFS): Tingling or burning, redness, flaking, bothersome swelling, small blisters, or small sores on palms of hands or soles of feet
  • Stomatitis: Painful redness, swelling, or sores in the mouth
  • Fever: A fever of 100.5oF or higher
  • Neutropenia: Low white blood cell count
  • Nausea, vomiting, tiredness, weakness, rash, shortness of breath, or mild hair loss
  • Loss of appetite
  • Diarrhea

Be sure to tell your doctor immediately if you experience any of these or other symptoms.

DOXIL may make the side effects of other anticancer therapies worse when used in combination.

Following administration, DOXIL may turn urine and other bodily fluids a reddish-orange color. This is due to the color of DOXIL and will go away as the drug leaves the body.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088 (1-800-332-1088).

Please click here for full Product Information in PDF format,for more details.

 


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