IV Preparation

 

DOXIL® is a translucent, red liposomal dispersion that must be reconstituted before use. Use the tabs below to learn how to properly prepare, store, handle, and dispose of DOXIL®.

  • Preparation
  • Storage
  • Proper handling
    and disposal

Preparation

  • Prior to administration, the appropriate dose of DOXIL® must be diluted in 5% Dextrose Injection, USP (D5W)
  • Do not substitue DOXIL® for doxorubicin HCl injection
  • Do not administer as an undiluted suspension or as an intravenous bolus
  • Do not mix with other drugs

Storage

  • Refrigerate unopened vials of DOXIL® at 2°C to 8°C (36°F to 46°F). Do not freeze.
  • Diluted DOXIL® should be refrigerated at 2°C to 8°C (36°F to 46°F) and administered within 24 hours

Proper handling and disposal

  • As with any cytotoxic agent, caution should be exercised in the handling, preparation, and disposal of DOXIL®
  • If DOXIL® comes into contact with skin or mucosa, immediately wash the affected area thoroughly with soap and water
  • Visually inspect reconstituted drug for particulate matter and discoloration prior to administration; do not use if precipitate or foreign matter is present